This recent Article highlights the progress made in brain science, our focus on solving grand world challenges, and the critical need to continue this advancement. The article describes how a paralyzed man using only his brain signals was able to operate, maneuver, and walk in a whole-body robotic exoskeleton. This press release provides more details. The findings could advance efforts to help paralyzed patients drive computers using brain signals alone; “perhaps starting with driving wheelchairs using brain activity instead of joysticks and progressing to developing an exoskeleton for increased mobility,” says Stephan Chabardes, neurosurgeon from the CHU of Grenoble-Alpes, France.